A diuretic-saluretic for prompt relief of edema associated with cardiac insufficiency and acute noninflammatory tissue edema.
- High potency for effective diuresis
- Predictable performance with high therapeutic index
- Rapid onset of diuresis with peak effect occurring within
15 to 30 minutes of intravenous administration1
- Furosemide, injectable solution, 5% (50 mg/mL)
SALIX® is a highly effective diuretic-saluretic which if given in excessive amounts may result in dehydration and electrolyte imbalance, enhancing the risk of circulatory collapse, thrombosis, and embolism. The animal should be observed for early signs of fluid depletion with electrolyte imbalance, and corrective measures should be administered. See package insert for full information regarding contraindications, warnings, and precautions. SALIX may lower serum calcium levels and cause tetany in rare cases of animals having an existing hypocalcemic tendency. Do not use in horses intended for human consumption.
SALIX is indicated for the treatment of peripheral edema, (pulmonary congestion, ascites) associated with cardiac insufficiency and acute noninflammatory tissue edema. It is an effective diuretic possessing a wide therapeutic range. Pharmacologically it promotes the rapid removal of abnormally retained extracellular fluids. The rationale for the efficacious use of diuretic therapy is determined by the clinical pathology producing the edema. The continued use of heart stimulants, such as digitalis or its glycosides, is indicated in cases of edema involving cardiac insufficiency.
Dose and Administration
For the horse, the individual dose is 250 mg to 500 mg (5 to 10 mL) administered intramuscularly or intravenously once or twice daily at 6 to 8 hour intervals until desired results are achieved. The veterinarian should evaluate the degree of edema present and adjust dosage schedule accordingly. Do not use in horses intended for human consumption.
The dosage should be adjusted to the individual’s response. In severe edematous or refractory cases, the dose may be doubled or increased by increments of 1 mg per pound body weight. The established effective dose should be administered once or twice daily. The daily schedule of administration can be timed to control the period of micturition for the convenience of the client or veterinarian. Mobilization of the edema may be most efficiently and safely accomplished by utilizing an intermittent daily dosage schedule, i.e., every other day or 2 to 4 consecutive days weekly.